TABLE 2.
Multivariable analysis of cause-specific survival with endometrial cancer (n = 6597)
| Survival (%) |
Multivariable |
||||
|---|---|---|---|---|---|
| Characteristics | No. | 5-yr | 10-yr | HR (95%CI) | P-value |
| Age (y) | |||||
| <60 | 1890 | 92.4 | 89.7 | 1 | |
| ≥60 | 4707 | 86.3 | 81.6 | 1.94 (1.63-2.32) | <0.001 |
| Ethnicity | |||||
| White | 5280 | 88.3 | 84.6 | 1 | |
| Non-White | 1317 | 86.9 | 81.3 | 1.26 (1.06-1.49) | 0.01 |
| Marital status | |||||
| Single | 837 | 90.0 | 85.4 | 1.01 (0.81-1.27) | 0.92 |
| Married | 3452 | 88.8 | 84.8 | 1 | |
| Others | 2308 | 86.3 | 82.3 | 1.07 (0.93-1.24) | 0.35 |
| Registry area | |||||
| West | 3221 | 88.2 | 83.9 | 0.87 (0.74-1.03) | 0.10 |
| Central | 1576 | 86.9 | 83.2 | 1 | |
| East | 1800 | 88.9 | 84.9 | 0.91 (0.75-1.10) | 0.31 |
| Year at diagnosis | |||||
| Before 2000 | 2050 | 87.8 | 83.9 | 1 | |
| 2000 and after | 4547 | 88.3 | 83.9 | 0.96 (0.82-1.12) | 0.57 |
| Grade | |||||
| 1-2 | 2025 | 93.4 | 89.6 | 1 | |
| 3 | 4572 | 85.6 | 81.4 | 3.15 (2.56-3.89) | <0.001 |
| Stage | |||||
| IA | 2548 | 89.7 | 86.1 | 1 | |
| IB | 4049 | 87.1 | 82.7 | 1.78 (1.52-2.07) | <0.001 |
| Size (cm) | |||||
| <2.0 | 488 | 93.6 | 91.6 | 1 | |
| ≥2.0 | 3440 | 87.1 | 82.2 | 1.89 (1.34-2.66) | <0.001 |
| Unknown | 2669 | 88.3 | 84.5 | 1.63 (1.16-2.30) | <0.001 |
| Surgery type | |||||
| Simple hyst | 5363 | 88.2 | 84.2 | 1 | |
| Others | 961 | 87.2 | 83.1 | 1.04 (0.86-1.27) | 0.68 |
| Pelvic lymphadenectomy | |||||
| Performed | 3606 | 86.6 | 82.8 | 1 | |
| Not performed | 2991 | 89.7 | 85.3 | 1.13 (1.10-1.56) | 0.003 |
| Adjuvant radiotherapy | |||||
| Received | 6388 | 88.4 | 84.3 | 1 | |
| Declined | 209 | 78.4 | 73.1 | 1.84 (1.34-2.51) | <0.001 |
hyst, hysterectomy; HR, hazard ratio; CI, confidence interval. Women with grade 1-2 stage IB disease who did not undergo pelvic lymphadenectomy and women with grade 3 stage IA-IB disease with or without pelvic lymphadenectomy were examined. Results of a Cox proportional hazard regression model for multivariable analysis are shown. All the listed covariates were entered in the final model. Significant P-values are emboldened.