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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Adv Healthc Mater. 2020 Jun 11;9(13):e1901812. doi: 10.1002/adhm.201901812

Figure 4.

Figure 4.

In vivo therapeutic efficacy of combination X-ray photodynamic therapy (PDT) and C. novyi-NT bacterial therapy using the nano-bio therapeutic emulsion in the PC3 mouse tumor model. (a) Gram and (b) TUNEL staining of tumor tissue subjected to the indicated treatments: control, nano-bio therapeutic emulsion only, and nano-bio therapeutic emulsion plus X-ray radiation. The inner part of the red and yellow dotted line represents the hypoxic tumor core. (c) Quantitative analysis of TUNEL staining results. The control means a group injected with PBS (n=4, *P<0.002).