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. 2020 Mar 9;22(9):1339–1347. doi: 10.1093/neuonc/noaa054

Table 3.

Adjusteda use of supportive care medications following diagnosis of BM by race (OR = odds ratio)

White African American OR [95% CI] P Hispanic OR [95% CI] P Asian OR [95% CI] P
Pain medications
 Non-opioid analgesics Ref 0.89 [0.66–1.20] 0.44 0.69 [0.46–1.05] 0.08 0.97 [0.70–1.34] 0.86
 Opioids Ref 0.96 [0.85–1.08] 0.48 1.09 [0.94–1.26] 0.24 0.86 [0.75–0.99] 0.04
Medications for neurological symptoms
 Anti-emetics Ref 0.75 [0.68–0.83] <0.001 0.91 [0.80–1.04] 0.16 0.83 [0.73–0.94] 0.004
 Anti-epileptics Ref 1.04 [0.92–1.18] 0.49 1.11 [0.95–1.29] 0.19 0.83 [0.71–0.97] 0.02
 Headache aids Ref 0.81 [0.73–0.90] <0.001 0.83 [0.73–0.94] 0.004 0.81 [0.72–0.92] 0.001
 Steroids Ref 0.84 [0.76–0.93] <0.001 0.90 [0.80–1.03] 0.12 0.81 [0.72–0.92] 0.001
 Cognitive aids Ref 0.78 [0.49–1.23] 0.28 1.17 [0.69–1.99] 0.56 1.04 [0.64–1.70] 0.88
Psychotropic medications
 Antidepressants Ref 0.68 [0.57–0.80] <0.001 0.78 [0.64–0.97] 0.02 0.67 [0.53–0.85] 0.001
 Anxiolytics Ref 0.68 [0.56–0.82] <0.001 0.63 [0.49–0.81] <0.001 0.62 [0.48–0.80] <0.001
 Antidelirium/antipsychotic agentsb Ref 1.21 [0.97–1.52] 0.09 0.57 [0.38–0.86] 0.008 1.23 [0.88–1.70] 0.22
Other
 Muscle relaxants Ref 0.92 [0.72–1.16] 0.48 0.85 [0.62–1.16] 0.30 0.60 [0.41–0.89] 0.01
 Psychostimulantsb,c Ref 0.14 [0.03–0.59] 0.007 0.15 [0.02–1.07] 0.06 0.93 [0.40–2.17] 0.87
 Sleep aids Ref 0.71 [0.61–0.83] <0.001 0.78 [0.64–0.94] 0.01 1.00 [0.83–1.20] 0.98
 Appetite stimulants Ref 0.85 [0.77–0.94] 0.002 0.87 [0.76–0.99] 0.04 0.87 [0.76–0.99] 0.03

aCovariates were adjusted for age, sex, marital status, ZIP code level high school completion rate and median household income, year of BM diagnosis, Charlson comorbidity index, and primary tumor site.

b,cCovariates for use of prior medication (b) and melanoma as primary cancer site (c) were removed from select models due to nonconvergence.