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. 2020 Feb 17;22(9):1379–1387. doi: 10.1093/neuonc/noaa042

Table 3.

Univariate analysis of parent proxy-reported HRQoL

Parameter (numbers) Parent-Proxy Reported PedsQL
Total Core Score Physical Score Psychosocial Score Emotional Score Social Score School Score
Distinction* or Correlation** Coefficient (P Value)
Age** 0.003 (0.99) 0.06 (0.73) -0.03 (0.84) -0.07 (0.67) 0.07 (0.66) -0.10 (0.55)
Sex: F vs M* 25/15 3.0 (0.64) 7.5 (0.33) 0.8 (0.89) 1.4 (0.83) -0.4 (0.96) -1.2 (0.87)
Race: Other vs Wh.* (3/37) 13.1 (0.26) 15.3 (0.28) 12.1 (0.29) 10.1 (0.40) 12.5 (0.37) 12.7 (0.31)
Income** 0.06 (0.72) 0.01 (0.93) 0.08 (0.63) -0.07 (0.69) 0.07 (0.68) 0.19 (0.25)
Ependymoma vs Other* (22/18) 1.5 (0.81) 0.8 (0.92) 2.1 (0.73) 5.3 (0.41) -0.3 (0.97) -0.1 (0.99)
Location: PF vs ST* 28/12 -2.1 (0.75) 1.1 (0.89) -3.9 (0.56) -6.2 (0.37) -5.2 (0.52) 1.1 (0.88)
Gastric tube* (33/7) 25.5 (<0.001) 31.6 (<0.001) 22.2 (0.003) 5.7 (0.49) 35.0 (<0.001) 25.9 (0.002)
EVD/shunt* 27/13 17.1 (0.007) 20.2 (0.008) 15.6 (0.012) 7.6 (0.25) 24.3 (0.001) 13.0 (0.06)
Chemotherapy* 16/24 2.6 (0.68) 1.1 (0.88) 3.4 (0.58) 1.5 (0.82) 7.2 (0.35) 0.1 (0.99)
IT/High dose* chemotherapy 30/10 1.7 (0.81) 0.3 (0.97) 2.8 (0.69) 4.2 (0.56) -2.7 (0.76) 3.6 (0.64)
Involved field vs CSI* 5/35) -4.3 (0.65) -4.5 (0.69) -4.0 (0.66) -5.3 (0.58) -9.3 (0.40) 1.2 (0.90)
PRT dose** 0.198 (0.22) 0.203 (0.21) 0.176 (0.28) 0.279(0.08) 0.073 (0.66) 0.149 (0.36)

Relationship assessed using the paired T-test for categorical variables*, and Pearson correlation coefficient for continuous variables**. Statistical significance measures are highlighted in bold.

Abbreviations: F, female; M, male; PF, Posterior Fossa, ST, Supratentorial, EVD, extraventricular drain; IT, intrathecal; CSI, craniospinal irradiation; PRT, proton therapy