Table 4.
Univariate analysis of child self-reported HRQoL
| Parameter (numbers) | Child Self-Reported PedsQL | |||||
|---|---|---|---|---|---|---|
| Total Core Score | Physical Score | Psychosocial Score | Emotional Score | Social Score | School Score | |
| Distinction* or Correlation Coefficient** (P value) | ||||||
| Age** | 0.01 (0.97) | -0.03 (0.87) | 0.03 (0.87) | 0.06 (0.71) | 0.18 (0.28) | -0.15 (0.38) |
| Sex*: F vs M 25/15 | 3.1 (0.53) | 1.1 (0.85) | 4.1 (0.40) | 3.5 (0.50) | 5.7 (0.34) | 3.1 (0.64) |
| Race*: Other vs Wh. (3/37) | 5.8 (0.51) | 9.5 (0.37) | 3.8 (0.67) | 6.1 (0.50) | 6.0 (0.59) | -0.8 (0.95) |
| Income** | 0.05 (0.78) | 0.06 (0.73) | 0.04 (0.83) | -0.03 (0.88) | -0.02 (0.93) | 0.11 (0.51) |
| Ependymoma vs Other* (22/18) | 1.9 (0.68) | 5.9 (0.30) | -0.2 (0.97) | -2.2 (0.65) | -2.0 (0.73) | 3.6 (0.57) |
| Location: PF vs ST* 28/12 | -0.5 (0.92) | 4.2 (0.50) | -3.1 (0.56) | -3.4 (0.53) | -3.5 (0.59) | -2.4 (0.74) |
| Gastric tube* (33/7) | 19.8 (<0.001) | 24.3 (<0.001) | 17.4 (0.003) | 7.9 (0.21) | 22.3 (0.002) | 22.0 (0.006) |
| EVD/shunt * 27/13 | 6.3 (0.20) | 5.6 (0.34) | 6.6 (0.18) | 1.3 (0.80) | 15.0 (0.012) | 3.6 (0.60) |
| Chemotherapy* 16/24 | 9.3 (0.046) | 9.5 (0.09) | 9.1 (0.05) | 6.9 (0.16) | 9.2 (0.12) | 11.3 (0.08) |
| IT/High dose chemotherapy* 30/10 | 4.9 (0.36) | 7.6 (0.23) | 3.4 (0.53) | 1.8 (0.74) | 2.2 (0.74) | 6.2 (0.39) |
| Involved field vs CSI* (35/5) | -2.6 (0.71) | -4.0 (0.64) | -1.9 (0.79) | 3.0 (0.68) | 2.1 (0.81) | -10.8 (0.26) |
| RT dose** | 0.044 (0.79) | 0.133 (0.42) | -0.018 (0.91) | 0.059 (0.72) | -0.156 (0.34) | 0.057 (0.73) |
Relationship assessed using the paired t-test for categorical variables,* and Pearson correlation coefficient for continuous variables.** Statistical significance measures are highlighted in bold.
Abbreviations: PF, posterior fossa, ST, supratentorial, EVD, extraventricular drain; IT, intrathecal; CSI, craniospinal irradiation; PRT, proton therapy.