TABLE 1.
Patient demographics and basal melanoma characteristics in the study population.
| Characteristics | Frequency | Percentage |
| Age at melanoma diagnosis (n = 305) | ||
| Median, 56 (range = 18–86) years | ||
| Sex (n = 305) | ||
| Male | 193 | 63.3 |
| Female | 112 | 36.7 |
| Primary site (n = 305) | ||
| Limbs | 82 | 26.9 |
| Head and neck | 39 | 12.8 |
| Trunk | 134 | 43.9 |
| Occult | 35 | 11.5 |
| Mucosa | 6 | 2.0 |
| Uvea | 9 | 3.0 |
| Histology (n = 239) | ||
| SSM | 88 | 36.8 |
| Nodular | 95 | 39.7 |
| Acral | 9 | 3.8 |
| Lentigo Maligna | 1 | 0.4 |
| Mucosal | 6 | 2.5 |
| Uveal | 9 | 3.8 |
| Other | 31 | 13.0 |
| Breslow depth (n = 239) | ||
| ≤1 mm | 28 | 11.7 |
| >1–2 mm | 48 | 20.1 |
| >2–4 mm | 73 | 30.5 |
| >4 mm | 90 | 37.7 |
| Ulceration (n = 239) | ||
| Present | 138 | 57.7 |
| Absent | 101 | 42.3 |
| Number of mitosis (n = 201) | ||
| ≤1 | 46 | 22.9 |
| >1 | 155 | 77.1 |
| Tumor-infiltrating lymphocytes (n = 169) | ||
| Brisk | 37 | 21.9 |
| Absent or not brisk | 132 | 78.1 |
| Lymph node mts (n = 263) | ||
| N0 | 133 | 50.6 |
| N+ | 130 | 49.4 |
| BRAF status (n = 285) | ||
| Mutated | 168 | 58.9 |
| Wild type | 117 | 41.1 |
| NRAS status (n = 59) | ||
| Mutated | 21 | 35.6 |
| Wild type | 38 | 64.4 |
| LDH levels (n = 105) | ||
| ≤2 × ULN | 82 | 78.1 |
| >2 × ULN | 23 | 21.9 |
LDH, lactate dehydrogenase; ULN, upper limit of normal; SSM, superficial spreading melanoma; mts, metastases.