Table 2.
Joint Model Results for the %FEV1 Submodel. Fixed Effects Estimates of Association of Covariates on Forced Expiratory Volume in 1 second as a Percentage of Predicted (%FEV1)
| Estimate (95% CI) | |
|---|---|
| Intercept at age 5 years | 88 (87, 89) |
| Agea | −1.5 (−1.6, −1.4) |
| Age squared | 0.013 (0.011, 0.015) |
| Birth year | 0.22 (0.15, 0.29) |
| Male | 0.90 (0.01, 1.8) |
| F508 alleles: 2 vs 0, 1 or not typed | −0.080 (−1.17, 1.01) |
| Age × male | 0.11 (0.08, 0.14) |
| Age × F508 alleles: 2 vs 0, 1 or not typed | −0.35 (−0.45, −−0.25) |
| Birth year × male | 0.059 (−0.027, 0.15) |
| Birth year × F508 alleles: 2 vs 0, 1 or not typed | −0.0040 (−0.067, 0.059) |
a
Age term corresponds to %FEV1 slope. The age × male term represents the age by sex interaction, i.e. the difference in slope for males compared with females
%FEV1 indicates percent forced expiratory volume.