Figure 1.

Anti-LOX combined with a VD induces penile lengthening (n = 6 per group). (a) Representative images of penile length. (b) Representative images of penile length after a 1-week washout period. For a and b, penile length was measured under unified vacuum device aspiration condition (measured at –200 mmHg for 5 min twice with a 2-min interval). (c) Exposed penile length; the length was measured from the junction of urethral bulb and corpus cavernosum (marked with yellow line), to tip of glans cartilage; the measurement errors of length data were corrected on recorded images. (d) Statistical analysis of penile length (P < 0.0001). (e) Statistical analysis of penile length after a 1-week washout period (P < 0.0001). (f) Statistical analysis for exposed penile length (P < 0.0001). Anti-LOX: intragastric administration of β-aminopropionitrile (BAPN) with a dose of 100 mg kg⁻¹ day⁻¹; VD: vacuum device aspiration with negative pressure of -300 mmHg. ^**P < 0.01, ^***P < 0.0001. LOX: lysyl oxidase.