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Validation of candidate LGA regions by bisulfite pyrosequencing. Bar charts representing the DNA methylation levels at five CpG sites and total CpGs overlapping CACNA1G (A), and three CpG sites and total CpGs overlapping GNAS (B) in LGA (red color) and controls (blue color) (Nonparametric Mann–Whitney T test; Data: mean ± SD; ∗: P < .05; ∗∗: P < .01). LGA = large for gestational age, DNA = deoxyribonucleic acid, GNAS = guanine nucleotide binding protein, alpha stimulating.
