TABLE II.
Response to 131I-MIBG by Tertiles of Whole-Body Radiation Dose
Alla | Tertile 1 | Tertile 2 | Tertile 3 | P-valueb | |
---|---|---|---|---|---|
Response | 57 (27%) | 21 (30%) | 19 (27%) | 17 (24%) | 0.45 |
No response | 156 (73%) | 50 (70%) | 52 (73%) | 54 (76%) | |
CR | 16 (8%) | 9 (13%) | 4 (6%) | 3 (4%) | |
PR | 42 (20%) | 13 (18%) | 15 (22%) | 14 (20%) | |
SD | 96 (46%) | 33 (47%) | 32 (46%) | 31 (44%) | 0.08 |
PD | 38 (18%) | 9 (13%) | 14 (20%) | 15 (21%) | |
MR | 18 (8%) | 6 (9%) | 4 (6%) | 8 (11%) |
Response for three patients was not evaluable;
Cochran–Mantel–Haenszel test. CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; MR, mixed response; ASCT, autologous stem cell transplant.