Table 1. Characteristics of subjects.
Test (n = 96) | Replication (n = 96) | Non-AD dementia (n = 95) | |||||
---|---|---|---|---|---|---|---|
Controls | AD | Controls | AD | DLB | VaDa | FTLDb | |
(n = 48) | (n = 48) | (n = 48) | (n = 48) | (n = 34) | (n = 40) | (n = 27) | |
Age, mean (SD) | 71.9 (3.7) | 72.7 (5.4) | 70.2 (1.5) | 70.5 (1.8) | 79 (5.4) | 79 (6.9) | 70.2 (8.8) |
Female, No (%) | 22 (46) | 24 (50) | 26 (54) | 24 (50) | 21 (62) | 15 (38) | 17 (63) |
MMSE score, mean(SD) | 28.5 (1.5) | 13.3 (5.1) | 29.4 (0.8) | 17.7 (3.8) | 16.7 (4.7) | 17.4 (4.8) | 16.6 (6.9) |
APOE ε4 homozygote, No. (%) | 1 (2.1) | 9 (19) | 0 (0) | 4 (8.3) | 3 (8.8) | 1 (2.6) | 0 (0) |
APOE ε4 heterozygote, No. (%) | 9 (19) | 22 (46) | 6 (13) | 28 (58) | 9 (26) | 7 (18) | 10 (37) |
APOE ε4 non-carriers, No. (%) | 38 (79) | 17 (35) | 42 (88) | 16 (33) | 22 (65) | 31 (79) | 17 (63) |
aThe MMSE score of one subject and the APOE genotype of another subject were not available.
bThe MMSE score of one subject was not available. Abbreviations: APOE ε4, the ε4 allele of APOE; ROC, receiver operating characteristic; AD, Alzheimer’s disease; DLB, dementia with Lewy bodies; VaD, vascular dementia; FTD, frontotemporal dementia.