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. 2020 Sep 29;15(9):e0239590. doi: 10.1371/journal.pone.0239590

Table 2. Potential factors associated with pneumonia onset.

pneumonia onset
  (+) (-) univariate analysis
Factors n = 17 n = 209 p value
Age, year 77.4 ± 9.5 72.4 ± 13.3 0.134
Gender (Female), n (%) 5 (29.4) 93 (44.5) 0.227
Body mass index, kg/m2 23.0 ± 4.1 23.3 ± 4.0 0.790
Stroke Subtypes 0.137
    ATBI, n (%) 2 (11.8) 36 (17.2)
    CEI, n (%) 1 (5.9) 22 (10.5)
    LI, n (%) 2 (11.8) 40 (19.1)
    Others, n (%) 6 (35.3) 85 (40.7)
    ICH, n (%) 6 (35.3) 26 (12.4)
Location of lesion
    frontal lobe, n (%) 4 (23.5) 68 (32.5) 0.443
    temporal lobe, n (%) 3 (17.7) 21 (10.1) 0.328
    parietal lobe, n (%) 2 (11.8) 32 (15.3) 0.694
    occipital lobe, n (%) 2 (11.8) 24 (11.5) 0.972
    insular cortex, n (%) 2 (11.8) 8 (3.8) 0.126
    corona radiata, n (%) 5 (29.4) 51 (24.4) 0.645
    basal ganglia, n (%) 8 (47.1) 44 (21.1) 0.014
    capsulae internae, n (%) 0 (0) 9 (4.3) 0.383
    thalamus, n (%) 3 (17.7) 21 (10.1) 0.328
    brain stem, n (%) 2 (11.8) 42 (20.1) 0.404
    cerebellum, n (%) 2 (11.8) 18 (8.6) 0.660
Past history
    Hypertension, n (%) 10 (58.8) 140 (67.0) 0.493
    Diabetes mellitus, n (%) 4 (23.5) 42 (20.1) 0.735
    Dyslipidemia, n (%) 3 (17.7) 32 (15.3) 0.798
    Atrial fibrillation, n (%) 1 (5.9) 19 (9.1) 0.654
    Stroke, n (%) 6 (35.3) 57 (27.3) 0.478
Current smoker, n (%) 2 (11.8) 49 (23.4) 0.268
Habitual drinker, n (%) 1 (5.9) 74 (35.4) 0.013
NIHSS score, median (minimum, maximum) 10 (0, 23) 2 (0, 19) <0.001
RSST<3 times /30 seconds, n (%) 11 (64.7) 26 (12.4) <0.001
MWST score<4, n (%) 5 (29.4) 10 (4.8) <0.001
Medication
    angiotensin-converting enzyme inhibitor, n (%) 3 (17.7) 18 (8.6) 0.217
    beta blocker, n (%) 4 (23.5) 32 (15.3) 0.373
    cilostazol, n (%) 4 (23.5) 45 (21.5) 0.847
Simplified cough test abnormal, n (%) 10 (58.8) 8 (3.8) <0.001

SD, standard deviation; ATBI, atherothrombotic brain infarction; CEI, cardiogenic embolism infarction; LI, lacunar infarction; ICH, intracerebral hemorrhage; NIHSS, National Institutes of Health Stroke Scale; RSST, repetitive saliva swallowing test; MWST, modified water swallowing test.