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. 2020 Sep 17;16(9):e1009036. doi: 10.1371/journal.pgen.1009036

Fig 4. Robustness of the ASD and PEITANG relationship.

Fig 4

Association between the ability to recognize angry faces in the middle proband group (ages 11–17) using the polygenic risk for autism spectrum disorder (ASD) covaried for age, sex, ten principal components, and the PRS for four brain imaging phenotypes, attention deficit hyperactivity disorder, schizophrenia, and educational attainment. (A) PRS p-value across a range of genome-wide significance (GWS) thresholds; the maximum PRS before and after covarying for all brain and psychiatry traits are labeled. (B) The positive correlation between quartiles of ASD polygenic risk and the number of correct responses to anger recognition trials in the Penn Emotional Intelligence Test; the lowest PRS quartile represents the referent.