Table 1. PNC sample description.

Samples sizes for each age group (defined by Philadelphia Neurodevelopmental Cohort) after quality control and selection of unrelated European samples.

Proband	Age, years	Male N	Female N	Total N	Phenotype N
Young	8–10	579	456	1,035	311
Middle	11–17	1,197	1,302	2,499	491
Adult	18 and over	345	430	775	324