Fig 5. Ratio of infectious spread to mitotic spread and number of new clones per day, by patient and estimator.

A Ratio of infectious spread to mitotic spread. B Number of new clones generated per day. Values of both the ratio and number of new clones are derived from estimators of infectious spread. In each plot, red crosses and bars respectively denote point estimates and the range from the nine estimates for each subject from the hybrid model. Upper bound approximations from r_I,Supremum (green triangles) are shown, together with tighter upper bounds from $r_{I,f_{\max }}$ (coloured circles) for multiple values of f_max between 1 and 1000. Lighter colours denote higher values of f_max. Hybrid model point estimates are very close to the estimates obtained for f_max = 1 (lowest circles). Estimates plotted on logarithmic scale.