TABLE 1.
Baseline characteristics and clinical presentation of women with pregnancy‐associated acute pulmonary embolism
| Parameters | Total women (N = 1839) | Women with haemodynamic failure a (n = 135) | Women without haemodynamic failure a (n = 1704) | Absolute risk difference (95% CI) |
|---|---|---|---|---|
| Age (years) | 31 (27–35) | 33 (30–37) | 31 (26–35) | — |
| In‐hospital stay (days) | 8 (4–14) | 10 (2–19) | 8 (5–14) | — |
| Duration of pregnancy | ||||
| <5 weeks | 11 (0.6%) | 0 (0.0%) | 11 (0.6%) | +0.0% (−4.5%; +6.6%) |
| 5–13 weeks | 193 (10.5%) | 15 (11.1%) | 178 (10.4%) | |
| 14–19 weeks | 60 (3.3%) | 3 (2.2%) | 57 (3.3%) | +0.2% (−4.5%; +6.9%) |
| 20–25 weeks | 155 (8.4%) | 13 (9.6%) | 142 (8.3%) | |
| 26–33 weeks | 407 (22.1%) | 18 (13.3%) | 389 (22.8%) | −13.8% (−20.4%; −5.9%) |
| 34–36 weeks | 224 (12.2%) | 11 (8.1%) | 213 (12.5%) | |
| 37–41 weeks b | 722 (39.3%) | 67 (49.6%) | 655 (38.4%) | +11.2% (+2.6%; +19.8%) |
| Clinical presentation, co‐morbidities, and provoking risk factors | ||||
| Surgery during the in‐hospital stay | 1251 (68.0%) | 119 (88.1%) | 1132 (66.4%) | +21.7% (+14.8%; +26.7%) |
| Obesity | 104 (5.7%) | 10 (7.4%) | 94 (5.5%) | +1.9% (−1.6%; +7.7%) |
| Heart failure | 80 (4.4%) | 19 (14.1%) | 61 (3.6%) | +10.5% (+5.5%; +17.4%) |
| Deep venous thrombosis or thrombophlebitis | 109 (5.9%) | 10 (9.2%) | 99 (5.8%) | +1.6% (−2.0%; +7.4%) |
| Preeclampsia | 139 (7.6%) | 10 (7.4%) | 129 (7.6%) | −0.16% (−3.8%; +5.6%) |
| Eclampsia | 17 (0.8%) | 3 (2.2%) | 14 (0.8%) | +1.4% (−0.2%; +5.5%) |
| HELLP syndrome | 30 (1.6%) | 3 (2.2%) | 27 (1.6%) | +0.6% (−1.0%; +4.8%) |
| In‐hospital stay (days) | 8 (4–14) | 10 (2–19) | 8 (5–14) | — |
| Systemic thrombolysis | 67 (3.6%) | 51 (37.8%) | 16 (0.9%) | +36.8% (+29.1%; +45.3%) |
| In‐hospital cumulative death rate | 63 (3.4%) | 50 (37.0%) | 13 (0.8%) | +36.3% (+28.6%; +44.7%) |