Table 2.
Patient characteristics at discharge
| Parameter | BNP−/WRF− | BNP−/WRF+ | BNP+/WRF− | BNP+/WRF+ | P value |
|---|---|---|---|---|---|
| n = 94 | n = 45 | n = 115 | n = 57 | ||
| Body weight at discharge (kg) | 59.7 ± 15.7 | 54.5 ± 17.2 | 55.0 ± 12.6 | 55.7 ± 13.9 | 0.09 |
| Coarse crackles at discharge, n (%) | 2 (2.1) | 1 (2.2) | 2 (1.7) | 0 (0.0) | 0.62 |
| Peripheral oedema at discharge, n (%) | 5 (5.3) | 2 (4.4) | 10 (8.7) | 5 (8.8) | 0.63 |
| CTR at discharge (%) | 53.6 ± 5.9 | 54.5 ± 6.3 | 56.2 ± 6.3 * | 58.3 ± 7.5 * ,† | 0.0001 |
| Length of hospital stay (days) | 16.1 ± 8.2 | 20.4 ± 18.5 | 16.6 ± 10.0 | 22.8 ± 13.9 * , ‡ | 0.002 |
| Laboratory data at discharge | |||||
| Albumin (g/dL) | 3.7 ± 0.4 | 3.6 ± 0.4 | 3.5 ± 0.5 * | 3.4 ± 0.4 * , † | <0.0001 |
| Blood urea nitrogen (mg/dL) | 20.0 ± 9.3 | 23.4 ± 9.0 | 22.8 ± 10.9 | 26.8 ± 14.5 * | 0.004 |
| Creatinine (mg/dL) | 0.98 ± 0.50 | 1.07 ± 0.44 | 1.08 ± 0.44 | 1.43 ± 1.01 * , † , ‡ | 0.0001 |
| eGFR (mL/min/1.73 m2) | 63.7 ± 17.8 | 53.4 ± 20.0 * | 55.7 ± 19.2 * | 46.6 ± 22.1 * , ‡ | <0.0001 |
| Sodium (mEq/L) | 137.9 ± 3.4 | 138.6 ± 2.3 | 139.3 ± 3.0 * | 137.8 ± 4.5 ‡ | 0.01 |
| Chloride (mEq/L) | 103.1 ± 3.8 | 104.5 ± 3.3 | 104.4 ± 4.0 | 103.6 ± 4.8 | 0.07 |
| Potassium (mEq/L) | 4.5 ± 0.4 | 4.5 ± 0.5 | 4.4 ± 0.4 | 4.5 ± 0.6 | 0.3 |
| Haemoglobin (g/dL) | 13.0 ± 2.4 | 11.9 ± 2.4 | 12.6 ± 2.3 | 11.5 ± 2.5 * , ‡ | 0.0009 |
| Haematocrit (%) | 38.7 ± 6.7 | 35.8 ± 6.6 | 37.8 ± 6.3 | 34.4 ± 6.9 * , ‡ | 0.0006 |
| BNP (pg/mL) | 143.7 ± 62.5 | 123.7 ± 62.6 | 667.3 ± 445.8 * , † | 734.8 ± 533.4 * , † | <0.0001 |
| Medication at discharge | |||||
| Beta‐blockers, n (%) | 70 (74.5) | 24 (53.3) | 88 (76.5) | 39 (68.4) | 0.03 |
| ACEI/ARBs, n (%) | 74 (78.7) | 32 (71.1) | 78 (67.8) | 29 (50.9) | 0.005 |
| Loop diuretics, n (%) | 68 (72.3) | 30 (66.7) | 93 (80.9) | 46 (80.7) | 0.18 |
| Aldosterone antagonists, n (%) | 31 (33.0) | 20 (44.4) | 40 (34.8) | 26 (45.6) | 0.3 |
ACEI, angiotensin‐converting enzyme inhibitor; ARB, angiotensin 2 receptor blocker; BNP, B‐type natriuretic peptide; CTR, cardiothoracic ratio; eGFR, estimated glomerular filtration rate; WRF, worsening renal function.
*
P < 0.05 compared with BNP−/WRF− group.
†
P < 0.05 compared with BNP−/WRF+ group.
‡
P < 0.05 compared with BNP+/WRF− group.