Figure 4.

Altered CD8⁺ T cell activation in the lamina propria of Ceacam1^−/− mice. Ceacam1^−/− and WT mice were orally infected with ~ 2 × 10⁹ CFU of C. rodentium or gavaged with PBS. At day 10 post infection, lamina propria cells of the colon were isolated and characterized by flow cytometry. (a) Percentage of living CD8⁺ T cells and MFI of (b) activation marker CD69, (c) L-Selectin (CD62L) and (d) GzmB. All data are presented as mean ± SEM. Statistics were performed using the Student’s t-test (*, p < .05; **, p < .01; ***, p < .001).