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. 2020 Jan 25;12(1):1704141. doi: 10.1080/19490976.2019.1704141

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© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 2. — Short-chain fatty acid concentrations and gut permeability before and after AXOS (n = 24) and placebo intervention (n = 24). Data are given as means ± SEM. Data were analyzed using 2-way repeated measure ANOVA with time (pre/post) and intervention as covariates. There are no differences between fecal (a) acetate (b) propionate, (c) butyrate or fasting and postprandial plasma (d) acetate, (e) propionate, (f) butyrate between groups as a result of intervention (time*intervention, ns). Urinary sugar excretions and ratios were compared with Wilcoxon signed-rank test pre vs. post within groups. There were no differences in urinary excretion rates of (g) 0–5 h sucrose (gastro-duodenal permeability) (h) 0–5 h Lactulose:Rhamnose ratio (small intestinal permeability) (i) 5–24 h Sucralose:Erytrithol ratio (colonic permeability). AXOS Arabinoxylan-Oligosaccharides, PLA placebo.