Figure 2.

Gastrointestinal C. jejuni loads in infected mice.

Microbiota-depleted IL-10^−/- mice were perorally infected either with the C.jejuni 81–176 wild-type strain (WT; black circles, n= 18), the isogenic pepP gene deletion mutant (ΔpepP; white circles, n= 20) or the pepP gene complemented strain (Compl; crossed circles, n= 24) on d0 and d1. C.jejuni loads were determined in luminal samples taken on d6 post-infection by culture and expressed as colony-forming units per g(CFU/g) for stomach, duodenum, ileum, and colon. Medians (black bars) and levels of significance (p-values) assessed by the Mann–Whitney Utest are indicated. Data were pooled from four independent experiments.