Figure 5.

Secreted intestinal pro-inflammatory mediators in C. jejuni infected mice.

Quantitative analytical data obtained from colon (top) and mesenteric lymph nodes (MLN, bottom) of mice infected with WT (black circles), ΔpepP (white circles) or pepP complemented strain (Compl; crossed circles) for (a, d) nitric oxide, (b, e) IFN-γ, and (c, f) TNF concentrations. These were measured in supernatants of ex vivo biopsies extracted on d6 post-infection. Uninfected controls received vehicle only (none, white diamonds). Medians (black bars), significance levels (p-values) determined by the Kruskal–Wallis test and Dunn’s post-correction and the numbers of analyzed mice (in parentheses) are indicated. Data were pooled from four independent experiments.