Table 3.
Changes of Joint Mobility and Pain Level of Patient with DF After Anlotinib Treatment
| Patients | Tumor Site | Involved Joint | RECIST 1.1 Response |
Pre/Post-Treated Pain Level (VAS) | Pre/Post-Treated Range of Motion (°) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Flexion | Extension | Abduction | Adduction | External Rotation | Internal Rotation | |||||
| 1 | Upper arm | Elbow | PR | 4/2 | 90/120 | 0/0 | NA | NA | NA | NA |
| 2 | Gluteal region | Hip | SD | 5/3 | 60/60 | 5/0 | 30/20 | 20/20 | 30/30 | 40/40 |
| 3 | Thigh | Hip | PD | 5/4 | 15/NA | 0/NA | 20/NA | 5/NA | 40/NA | 40/NA |
| 4 | Popliteal region | Knee | SD | 5/3 | 50/90 | 20/15 | NA | NA | 30/30 | 10/10 |
| 5 | Hand | MCP joint | PR | 6/1 | 30/70 | 5/30 | NA | NA | NA | NA |
| 6 | Forearm | Wrist | SD | 6/2 | 20/50 | 10/30 | NA | NA | 25/50a | 40/60b |
| 7 | Gluteal region | Hip | PR | 5/3 | 60/90 | 0/10 | 15/20 | 10/20 | 30/40 | 30/40 |
| 8 | Gluteal region | Hip | SD | 6/1 | 90/130 | 10/20 | 10/30 | 20/20 | 40/40 | 40/40 |
| 9 | Upper arm | Elbow | PR | 7/1 | 60/110 | 10/0 | NA | NA | NA | NA |
| 10 | Hand | MCP joint | SD | 4/3 | 40/60 | 10/20 | NA | NA | NA | NA |
| 11 | Upper arm | Elbow | SD | 3/0 | 80/120 | 20/5 | NA | NA | NA | NA |
| 12 | Popliteal region | Knee | SD | 6/2 | 90/130 | 10/0 | NA | NA | 30/30 | 10/10 |
| 13 | Upper arm | Elbow | PR | 3/0 | 110/130 | 10/5 | NA | NA | NA | NA |
| 14 | Upper arm | Elbow | PR | 7/1 | 60/130 | 5/0 | NA | NA | NA | NA |
| 15 | Thigh | Knee | PD | 4/3 | 60/NA | 10/NA | NA | NA | 30/NA | 10/NA |
| 16 | Gluteal region | Hip | SD | 3/1 | 100/100 | 10/10 | 10/10 | 20/20 | 40/40 | 40/40 |
| 17 | Scapular region | Shoulder | PR | 6/2 | 50/90 | 20/40 | 30/60 | 10/40 | 40/60 | 50/70 |
| 18 | Foot | MTP joint | PD | 5/6 | 20/NA | 15/NA | NA | NA | NA | NA |
| 19 | Scapular region | Shoulder | SD | 6/3 | 70/70 | 10/10 | 20/20 | 20/20 | 30/30 | 70/70 |
| 20 | Upper arm | Elbow | PR | 5/1 | 90/110 | 30/10 | NA | NA | NA | NA |
| 21 | Axillary region | Shoulder | SD | 4/2 | 90/90 | 30/40 | 40/50 | 30/30 | 10/20 | 30/40 |
Notes: aMeans range of pronation. bMeans range of supination.
Abbreviations: NA, not achieved, MCP, metacarpophalangeal; MTP, metatarsophalangeal.