TABLE 3.
Clinical characteristics, medical history, and prognosis in the present study compared with previous studies in Western countries and in Japan
| Country sample size |
Present study, Japan n = 129 |
Sekijima Y., Japan 14 n = 51 |
Connors L. H., USA 6 n = 121 |
Gonzalez‐Lopez E., Spain/Italy 8 n = 108 |
|---|---|---|---|---|
| Age at diagnosis (years) | 78.5 ± 6.4 | 73.6 ± 9.2 | 75.1 (59.0–87.5) | 78.6 ± 8 |
| Male (%) | 85% | 80% | 98% | 81% |
| Past AF (%) | 47% | 18% | 67% | 56% |
| Past CTS (%) | 54% | 45% | 46% | 33% |
| NYHA III or IV (%) | 40% | — | 85% (II–IV) | 32% |
| Major manifestationleading diagnosis (%) | HF (61%) | HF (69%) | HF (86%) | HF (68%) |
| Cardiac troponin (ng/mL) | 0.056(0.040–0.089) a | 0.076 ± 0.042 a | 0.126(0.020–1.198) b | — |
| BNP (pg/mL) | 288 (181–464) | — | 482 ± 337 | — |
| NT‐proBNP (pg/mL) | — | 5872 ± 7584 | — | 2997 (1592–9621) |
| LVEF (%) | 53.2 (44.5–59.7) | 49.7 ± 13.8 | 48.1 ± 10.5 | 52 ± 14 |
| LVEF < 50% | 41% | 59% (EF < 55) | — | 37% |
| IVSTd | 15.7 ± 2.7 | 16.4 ± 4.1 | 16.3 ± 3.0 | 17.5 ± 3 |
| E/e′ | 20.6 (16.1–25.7) | 23.6 ± 11.5 | 20.5 ± 8.6 | — |
| Low voltage in ECG (%) | 36% | 33% | 33% | 22% |
| Median survival (month) | 58.9 | — | 46.7 | — |
| 3/5 years' survival rate | 69%/48% | — | —/36% | 74%/— |
Data are presented as median [inter‐quartile range], mean ± standard deviation, or n (%). For other abbreviations, see Table 1 .
ECG, electrocardiogram.
a
Measured by high‐sensitivity cardiac troponin T.
b
Measured by high‐sensitivity cardiac troponin I.