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. 2020 Jan 19;11(4):820–841. doi: 10.1080/19490976.2019.1710092

Figure 1.

Figure 1.

Antibiotic therapy, but not increased folate, reduces gastric pathology of INS-GAS mice at 18 WPI. (a) Timeline describing the experimental design and clinical interventions in this study. (b) Complete eradication of H. pylori in cohorts receiving antibiotic therapy was measured by qPCR. Antibiotic-free mice remained infected with high levels of H. pylori, and bacterial levels were unaffected by folate. (c) Histopathologic scoring of gastric pathology shows decreased gastric pathology dependent on antibiotic treatment but not folate supplementation. *P ≤ .05; **P ≤ .01; ***P ≤ .001.