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. 2020 Aug 17;12(1):1801301. doi: 10.1080/19490976.2020.1801301

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© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Effect of type of sweetener and the dietary fat content on the epithelium barrier and the inflammatory pathway. (a) Colon histological morphology by hematoxylin-eosin staining, (b) Epithelium layer quantitative analysis, (c) Western blot analysis of TLR4, TLR2, NFκB and occludin in the intestine (d) Serum LPS concentrations, (e) Serum IL-10 concentrations, (f) Serum sIgA concentrations and (g) Serum TNF-α concentrations after the consumption of different types of sweeteners with or without a high-fat diet. The raw data and means±SEMs are shown in each plot, n = 6–7 in each group. W = water, S = sucrose, F = fructose, G = glucose, SG = steviol glycosides, BS = brown sugar, H = honey, SV = steviol glycosides+sucrose and SU = sucralose.