Table 3.
Hematological changes and comparison of mice with and without Salmonella infection.
Red Blood Cells (106/mm3) |
White Blood Cells (103/mm3) |
Platelets (105/mm3) |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Day | Control | Infection1 | LC2 | LC+mcra 3 | Control | Infection | LC | LC+mcra | Control | Infection | LC | LC+mcra |
14 | 10.15 ± 0.14*b | 13.03 ± 4.20a | 10.84 ± 0.55b | 10.60 ± 0.46b | 3.48 ± 0.35a | 2.95 ± 0.80b | 3.12 ± 0.61a | 3.55 ± 0.42a | 7 ± 3a | 2 ± 2c | 5 ± 2b | 7 ± 3a |
21 | 10.34 ± 0.21b | 14.89 ± 3.87a | 10.72 ± 0.65b | 10.51 ± 0.33b | 3.65 ± 0.25a | 2.96 ± 0.40b | 3.13 ± 0.69a | 3.54 ± 0.38a | 8 ± 1a | 2 ± 1c | 5 ± 2b | 8 ± 3a |
28 | 10.29 ± 0.13c | 15.64 ± 4.37a | 11.84 ± 2.14b | 10.71 ± 0.53c | 3.59 ± 0.22a | 2.90 ± 0.49b | 3.26 ± 0.30a | 3.51 ± 0.29a | 7 ± 2a | 2 ± 1c | 4 ± 2b | 8 ± 2a |
1Mice with no probiotic protection infected with Salmonella Typhimurium
2Mice pre-administered with wild-type Lactobacillus casei followed by S. Typhimurium infection
3Mice pre-administered with mutant L. casei followed by S. Typhimurium infection
*Means with different letters (a-c) for each type of blood cells (red blood cell, white blood cell, and platelets) in different groups (control, infection, infection following LC pretreatment, and infection following LC+mcra pretreatment) at individual time point (day 14, 21, and 28) are significantly different at p < 0.05