Table 4.
White Blood Cells | Group | Day |
||
---|---|---|---|---|
14 | 21 | 28 | ||
Neutrophils (K/µL) |
Control | 1.31 ± 0.40*a | 1.34 ± 0.40a | 1.50 ± 0.21a |
Infection1 | 0.78 ± 0.36b | 0.41 ± 0.22b | 0.27 ± 0.14b | |
LC2 | 1.02 ± 0.30ab | 1.07 ± 0.37ab | 1.08 ± 0.48ab | |
LC+mcra 3 | 1.27 ± 0.56a | 1.16 ± 0.11ab | 1.20 ± 0.23ab | |
Lymphocytes (K/µL) |
Control | 2.19 ± 0.22a | 2.50 ± 0.13a | 2.44 ± 0.41a |
Infection | 1.18 ± 0.25b | 0.92 ± 0.15b | 0.73 ± 0.18b | |
LC | 2.05 ± 0.78a | 2.03 ± 0.13ab | 1.82 ± 0.26a | |
LC+mcra | 2.37 ± 0.37a | 2.53 ± 0.15a | 2.46 ± 0.52a | |
Monocytes (K/µL) |
Control | 0.04 ± 0.01b | 0.04 ± 0.02b | 0.04 ± 0.02c |
Infection | 0.16 ± 0.04a | 0.14 ± 0.06a | 0.19 ± 0.04a | |
LC | 0.05 ± 0.02b | 0.06 ± 0.03b | 0.08 ± 0.03b | |
LC+mcra | 0.05 ± 0.02b | 0.05 ± 0.02b | 0.05 ± 0.01c | |
Eosinophils (K/µL) |
Control | 0.06 ± 0.04b | 0.07 ± 0.03c | 0.07 ± 0.03b |
Infection | 0.16 ± 0.03a | 0.16 ± 0.04a | 0.17 ± 0.05a | |
LC | 0.09 ± 0.04b | 0.11 ± 0.01b | 0.09 ± 0.03b | |
LC+mcra | 0.07 ± 0.03b | 0.06 ± 0.03c | 0.06 ± 0.04b | |
Basophils (K/µL) |
Control | 0.01 ± 0.01c | 0.01 ± 0.01c | 0.01 ± 0.01c |
Infection | 0.03 ± 0.01a | 0.03 ± 0.02a | 0.04 ± 0.02a | |
LC | 0.02 ± 0.01b | 0.02 ± 0.01b | 0.02 ± 0.01b | |
LC+mcra | 0.01 ± 0.01c | 0.01 ± 0.01c | 0.01 ± 0.01c |
1Mice with no probiotic protection infected with S. Typhimurium
2Mice pre-administered with wild-type L. casei followed by S. Typhimurium infection
3Mice pre-administered with mutant L. casei followed by S. Typhimurium infection
*Means with different letters (a-c) for each type of WBC (neutrophils, lymphocytes, monocytes, eosinophils, and basophils) in different groups (control, infection, infection following LC pretreatment, and infection following LC+mcra pretreatment) at individual time point (day 14, 21, and 28) are significantly different at p < 0.05