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. 2020 Jun 9;11(6):1745–1757. doi: 10.1080/19490976.2020.1766936

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© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 6. — Coordinated colonic contractions are regulated by Bt.

Raw traces showing manometric pressure recordings in the whole colon in SPF (a), GF (b) and Bt-CONV (c). The number of colonic migrating motor complexes (CMMCs)/min is significantly increased in GF conditions compared to SPF and further upregulated in Bt-CONV compared to GF conditions (d). The frequency of contractions (peaks/min) is only increased in Bt-CONV compared to SPF and GF only in the proximal colon. The amplitude of contractions across all colonic regions and mouse groups is unchanged. N = 5. Error bars show SEM, and significance is p < .05 as denoted by *.