Table 2.
Characteristics of 75 Hirschsprung disease patients in the case–control study.
| Characteristic | Postoperative HAEC cases (n = 25) | Controls (n = 50) | P |
|---|---|---|---|
| Gestational age, weeks, mean (SD) | 39.2 (1.4) | 39.4 (1.1) | 0.55a |
| Birth weight, kg, mean (SD) | 3.5 (0.5) | 3.5 (0.5) | 0.87a |
| Gender, No. (%) | 0.07b | ||
| Female | 2 (8.0) | 13 (26.0) | |
| Male | 23 (92.0) | 37 (74.0) | |
| Mode of delivery, No. (%) | 0.19b | ||
| Cesarean | 16 (64.0) | 24 (48.0) | |
| Vaginal | 9 (36.0) | 26 (52.0) | |
| HSCR classificationc, No. (%) | 0.87b | ||
| Classical segment HSCR | 15 (60.0) | 29 (58.0) | |
| Long segment HSCR or total colonic aganglionosis | 10 (40.0) | 21 (42.0) | |
| Ostomy, No. (%) | 1.00d | ||
| No | 22 (88.0) | 43 (86.0) | |
| Yes | 3 (12.0) | 7 (14.0) | |
| Age at pull-through procedure, No. (%) | 0.47d | ||
| ≤180 days | 21 (84.0) | 45 (90.0) | |
| >180 days | 4 (16.0) | 5 (10.0) | |
| Surgical approach, No. (%) | 0.97b | ||
| Open pull-through | 3 (12.0) | 7 (14.0) | |
| Totally transanal endorectal pull-through | 13 (52.0) | 25 (50.0) | |
| Laparoscopic-assisted transanal pull-through | 9 (36.0) | 18 (36.0) |
aCalculated using t-test.
bCalculated using χ2 test.
cHSCR is classified as classical segment HSCR when the aganglionic segment does not extend beyond the upper sigmoid, long-segment HSCR when the aganglionic segment extends to the splenic flexure or transverse colon, and total colonic aganglionosis when the aganglionic segment extends to the colon and a short segment of the terminal ileum.
dCalculated using Fisher’s exact test.
Abbreviations: HAEC, Hirschsprung-associated enterocolitis; HSCR, Hirschsprung disease; SD, standard deviation.