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. 2020 Sep 11;12(1):1799733. doi: 10.1080/19490976.2020.1799733

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© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Influence of strains with and without encoded virulence factors on cellular growth rates. B. fragilis (a), Fusobacteriaceae (b), Enterobacteriaceae (c) and Clostridiales (d) encoding the virulence factors bft, fadA, any toxin (Map, pks, ShEt1, Stx2A), and any toxin (TcdA, TcdB, alpha-toxin), respectively, were compared to strains without these encoded virulence factors (Mann-Whitney U test). A trend toward cell growth enhancement was observed for B. fragilis bft+ secretomes (p = .07) (A), while significant inhibition of cell growth was observed for fadA+ Fusobacteriaceae cells (p < .0001), and secretomes (p < .05) (B), for Enterobacteriaceae secretomes encoding toxins (p < .0001) (C), and for Clostridiales secretomes encoding toxins (p < .0001) (D).