Figure 6. Identification of an immunoedited tumor cell expression signature.

(A) Unsupervised hierarchical clustering of differentially expressed genes identifies 6 main clusters, of which 4 represent genes differentially up- or downregulated in tumors in WT mice versus Pfp^–/– Rag2^–/– mice. (B) GO and KEGG pathway analysis of genes upregulated in the 4 clusters.