Figure 7. Correlations between circulating hormones and inflammatory proteins.

(A) Fold changes of proteins that significantly changed after BCG vaccination in males were correlated to baseline testosterone, adiponectin, leptin, and resistin concentrations. Only proteins with a significant correlation with one of the hormones are depicted in this figure. *P < 0.05, **P < 0.01, ***P < 0.001 by Spearman’s correlation. The color represents the strength and the direction of the correlation. (B) Spearman’s correlation between testosterone at baseline and fold change in CXCL1 2 weeks after vaccination is shown as an example.