Table 1.

Characteristics of the IgG4-RD patients according to history of malignancy^*

Variable	All (n = 125)	No history of malignancy (n = 105)	History of malignancy (n = 20)	P
Age at IgG4-RD onset, mean ± SD years	50.3 ± 14.9	48.5 ± 14.3	59.8 ± 14.6	0.002
Male sex	76 (60.8)	61 (58.1)	15 (75)	0.2
White race	96 (77)	77 (73)	19 (95)	0.04
Disease duration prior to evaluation, median (IQR) years	2 (1–6)	2.5 (1–6)	1 (0.5–4.5)	0.14
No. of involved organs, mean ± SD	2.3 ± 1.3	2.3 ± 1.4	2.4 ± 1.1	0.7
Serum IgG4, median (IQR) mg/dl†	140 (55.1–408)	121 (49.8–319)	407.5 (139–655)	0.03
Organ involvement
Submandibular gland	35 (28)	30 (29)	4 (20)	0.6
Lymph nodes	34 (27)	29 (28)	5 (25)	1
Orbit	28 (22)	23 (22)	4 (20)	1
Pancreas	24 (19)	20 (19)	4 (20)	1
Retroperitoneum	25 (20)	21 (20)	4 (20)	1

^*Except where indicated otherwise, values are the number (%). IgG4-RD = IgG4-related disease; IQR = interquartile range.

^†Among patients with active disease at the initial visit.