Table 1.

Summary of SARS-CoV-2 serology assay configuration, instruments, and interpretation

Instrument	Assay name	SARS-CoV-2 serology assay configuration	Interpretation for signal values
Abbott Architect i4000SR	Abbott SARS-CoV-2 IgG antibody	Chemiluminescent immunoassay detecting IgG antibodies to nucleocapsid protein	<1.4: Non-reactive≥1.4: Reactive
Roche Cobas E411	Elecsys Total Anti-SARS-CoV-2 antibody	Sandwich immunoassay detecting antibodies (IgM/IgG) to nucleocapsid protein	<1.0: Non-reactive≥1.0: Reactive
Beckman Unicel DxI 800	Access SARS-CoV-2 IgG antibody	Chemiluminescent immunoassay detecting IgG specific to RBD of S1 protein	<0.8: Non-reactive≥0.8 to <1.0: Equivocal≥1.0: Reactive
ADVIA Centaur XPT	Siemens SARS-CoV-2 Total antibody	One-step sandwich immunoassay detecting antibodies (IgM/IgG) to RBD of S1 protein	<1.0: Non-reactive≥1.0: Reactive
VITROS 3600	Vitros OCD Anti-SARS-CoV-2 Total antibody	Chemiluminescent immunoassay detecting antibodies (IgA, IgG, IgM) to S1 protein.	<1.0: Non-reactive≥1.0: Reactive
Evolis Complete System	cPass SARS-CoV-2 neutralising antibody ELISA	Blocking ELISA detection. HRP conjugated with recombinant RBD and human ACE-2 protein. Protein-protein interaction between HRP-RBD and ACE-2 are blocked by neutralising antibodies	Calculated as inhibition %<20%: Non-reactive≥20%: Reactive

HRP, horseradish peroxidase; RBD, receptor binding domain.