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. 2020 Jul 20;123(7):1101–1113. doi: 10.1038/s41416-020-0996-2

Fig. 4. Single-agent dose–response for ALKi in diagnosis and relapse eIMS xenografts.

Fig. 4

Tumour growth curves, PPTC objective response and Kaplan–Meier survival analysis of diagnosis and relapse eIMS xenografts treated with ad crizotinib or eh ceritinib. Vehicle-control groups are three to six mice and treatment groups are four to six mice. *: Comparison of treatment group to vehicle-control group. #: Comparison to lowest dose treatment group. γ: Comparison of highest dose treatment group to middle dose treatment group. *P < 0.05, **P < 0.01, (Mantel–Cox Test).