Figure 5.

Kinetic trends of amyloid aggregation in the presence of HyCar derivatives. Kinetic profiles of Aβ₄₂ aggregation alone (CTRL, 15 µM), incubated with the (a) Hy(200) derivatives of Car (HyCar(200)7, HyCar(200)10, HyCar(200)14) or their parent compounds (Hy(200), Car or a mixture) or (b) with the Hy(700) derivative of Car (HyCar(700)35), their parent compounds (Hy(700), Car or a mixture). The concentrations of the tested compounds were as follows: (a) 10 µM (Hy(200), HyCar(200)7, HyCar(200)10, HyCar(200)14), 700 µM (Car), (b) 0.4 µM (Hy(700), HyCar(700)35) or 270 µM (Car). The concentration values of Hy and Car in the Hy(200) + Car mixture are equivalent to the amount of Hy and Car units in the sample containing HyCar(200)14, whereas the concentration values of Hy and Car in the Hy(700) + Car mixture are equivalent to the amount of Hy and Car units in the sample containing HyCar(700)35.