Figure 8.

Aβ-induced toxicity in vitro in the presence of HyCar derivatives and their parent compounds. Viability of neuroblastoma SH-SY5Y cells after 24 h of incubation with differently pre-incubated Aβ₄₂ (6, 24, 48 h) in the absence or presence of HyCar derivatives (HyCar(200)14, HyCar(700)35), the parent polymeric compounds (Hy(200) and Hy(700)) or a mixture of the latter with Car ((Hy(200) + Car and Hy(700) + Car). The results are presented as the mean ± SD with 3 replicas for each condition (* = p ≤ 0.05; ** = p ≤ 0.005; *** = p ≤ 0.001 with respect to the untreated control; § = p ≤ 0.05; §§ = p ≤ 0.005; §§§ = p ≤ 0.001 with respect to Aβ treatment).