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. 2020 Jun 17;123(7):1123–1130. doi: 10.1038/s41416-020-0940-5

Fig. 4. Control of cell migration and invasion by miR-17-5p.

Fig. 4

a, b Over-expression of miR-17-5p and silencing of vimentin decreased LoVo and HT29 cell mobility. Left: The width of the scratch-wounded cell monolayer was recorded at 0 and 24 h, or 0 and 30 h after wounding via photography. Right: The relative migration distance presented in the column chart. c, d Down-regulation of miR-17-5p increased cell migration in LoVo and HT29. e Over-expression of miR-17-5p and silencing of vimentin inhibited LoVo cell invasion based on Transwell assays. f Down-regulation of miR-17-5p increased cell invasion in LoVo. The bars represent mean ± SD. *P < 0.05. All the experiments were repeated three times.