Table 1.

Descriptive analysis for all biomarkers in controls and mitochondrial patients

Biomarker		Mean	95% CI	Median	Standard deviation	Min	Max
Ccf-mtDNA MT-ND2 (copies/ul)	CTRLS	72.94	56.01–89.87	52.27	47.74	8.97	163.43
	MD	123.00	99.75–146.24	75.17	118.93	11.85	580.55
Creatine (umol/l)	CTRLS	6.92	4.79–9.06	6.85	5.61	0.00	19.07
	MD	12.11	9.52–14.69	11.16	10.83	0.00	50.91
FGF21 (pg/ml)	CTRLS	990.61	630.91–1350.31	659.39	909.29	88.52	3348.35
	MD	1765.76	1438.07–2093.44	1416.10	1374.26	0.00	7199.68
GDF-15 (pg/ml)	CTRLS	459.39	385.09–523.70	404.30	164.13	259.52	913.29
	MD	3712.74	2757.78–4667.79	2238.64	4004.98	318.65	25867.10

CTRLS controls, MD mitochondrial disease patients, CI confidence interval, Min minimum value, Max maximum value