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Methacholine-induced airway hypersensitivity (enhanced pause, i.e., Penh) in a) wild-type study groups. Values for Fig. 3a are expressed as mean ± SEM, *p < 0.05 compared to WT CON; #p < 0.05 compared to WT SEN, n = 6 mice per group, and b) A2AKO study groups. Values for Fig. 3b are expressed as mean ± SEM, *p < 0.05 compared to A2AKO CON, n = 6 mice per group
