Fig. 3.
Involvement of A2AR on reserpine-induced TJM and ROS production. a Dose-response curve of A2AR antagonist SCH58261 (0.001; 0.01 and 0.1 mg/kg) in reserpine-induced oral tremor (TJM). b SCH58261 (0.01 mg/kg) plus GUO (5 mg/kg) effect on reserpine-induced TJM. c SCH58261 (0.01 mg/kg) and GUO (5 mg/kg) effect on ROS increase in striatal slices of reserpinized mice. Results are presented as means ± SEM (*P < 0.05 vs control; #P < 0.05 vs reserpine; one-way ANOVA with Tukey’s post hoc test; n = 8–10)