Fig. 2.

Suppression of circ_0068655 alleviated hypoxia-induced cell injury. A The expression of circ_0068655 in HCMs transfected with shRNAs to knockdown circ_0068655 (sh-Circ_0068655#1, sh-Circ_0068655#2) or empty vector (sh-Ctrl) was determined by qRT-PCR. B Cell viability, C caspase-3 activity, D DNA fragmentation, E migration, and F invasion were evaluated by MTT assay, Caspase-3 activity assay, cell death ELISA (POD) assay, and trans-well assay in HCMs transfected with shRNAs against Circ_0068655 or empty vector (sh-Ctrl), respectively. The data are expressed as the mean ± SD. *p < 0.05; **p < 0.01