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. 2020 Jul 8;16(3):347–366. doi: 10.1007/s11302-020-09711-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Pyrimidine metabolism signaling pathway is highly enriched in lung cancer. a Table showed the detailed GEO datasets and TCGA datasets used in this study. b Enrichment plots demonstrated the enriched pyrimidine metabolism signaling pathway in GSE7670, GSE10072, GSE18842, GSE19188, GSE27262, GSE30219, GSE31210, GSE31908, GSE33532, GSE75324, and TCGA LUAD, LUSC datasets. Enrichment of normalized enrichment score (NES) and P values were presented. LUAD: lung adenocarcinoma; LUSC: lung squamous cell carcinoma;