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. 2020 Jul 8;16(3):347–366. doi: 10.1007/s11302-020-09711-4

Fig. 11.

Fig. 11

Pyrimidine metabolic rate limiting enzymes are up-regulated in multiple types of tumor. Heatmaps demonstrated the expression levels (log2 count) of pyrimidine metabolic rate limiting enzymes in normal and tumor samples in BLCA, BRCA, COAD, ESCA, KIRP, LIHC, LUSC, STAD, and THCA. Upregulated (red), downregulated (green), and unchanged (black) genes were delineated. BLCA, bladder urothelial carcinoma; BRCA, breast invasive carcinoma; COAD, colon adenocarcinoma; ESCA, esophageal carcinoma; KIRP, kidney renal papillary cell carcinoma; LIHC, liver hepatocellular carcinoma; LUSC, lung squamous cell carcinoma; STAD, stomach adenocarcinoma; THCA, thyroid cancer