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. 2020 Jul 8;16(3):347–366. doi: 10.1007/s11302-020-09711-4

Fig. 2.

Fig. 2

Pyrimidine metabolic rate limiting enzymes are up-regulated in lung cancer cells across different datasets. Heatmaps demonstrated the expression levels of pyrimidine metabolic rate–limiting enzymes in normal lung tissues and lung cancer tissues in GSE7670, GSE10072, GSE18842, GSE19188, GSE27262, GSE31908, GSE33532, GSE75324, and TCGA LUAD datasets. Upregulated (red), downregulated (green), and unchanged (black) genes were delineated. The expression levels of β-actin (ACTB) in normal and cancer tissues were used as control