Skip to main content
. Author manuscript; available in PMC: 2021 Oct 2.
Published in final edited form as: Anal Chim Acta. 2020 May 24;1132:134–155. doi: 10.1016/j.aca.2020.05.051

Figure 11. Labeling of glycosphingolipids by isotopic permethylation.

Figure 11.

Shown here are the conversions of all active protons (−OH and −NH) using isotopically labeled methyl iodide (MeI) in the form of 12C, 13C, or 2H in the presence of alkali hydroxide (commonly, NaOH) and an aprotic solvent (dimethyl sulfoxide) under anhydrous conditions.