Figure 1.

Illustration of the AR splice variant transcript nomenclature, functional annotation, exon compositions and specific peptide sequences. (A) AR gene structure with canonical and cryptic exon splice junctions marked according to GRCh37/hg19 human genome sequences (not drawn to scale); (B) Nomenclature, functional annotation, exon compositions, and variant-specific mRNA (color matched to A) and peptide sequences (in gray). Modified from Reference [26] with addition of novel AR variants with unconventional exons (in gold) from structural rearrangements. AR, androgen receptor.