Table 1.
Official licensed inactivated EV-A71 vaccines by the Chinese Food and Drug Administration.
| Organizations | Sinovac Biotech Co., Ltd | Beijing Vigoo Biological Co., Ltd | Chinese Academy of Medical Sciences |
|---|---|---|---|
| EV-A71 Strain | H07 (C4) | FY (C4) | M01 (C4) |
| Inactivation technique | Formalin | Formalin | Formalin |
| Cell substrate | Vero cells | Vero cells | Human diploid KMB-17 cell |
| Dosages | 400 U, two-dose | 320 U, two-dose | 100 U, two-dose |
| Adjuvant | Aluminum hydroxide | Aluminum hydroxide | Aluminum hydroxide |
| Population target | Children (6–35 month) | Children (6–35 month) | Children (6–71 month) |
| Enrollment | 10,077 | 10,245 | 12,000 |
| References | NCT01507857 | NCT01508247 | NCT01569581 |