Table 4.
Selvester score and fragmented QRS univariable and multivariable analysis for the primary endpoint (response to CRT).
| Univariable binary logistic regression | Multivariable ∗ | |||||
|---|---|---|---|---|---|---|
| O.R. | 95% C.I. | pvalue | O.R. | 95% C.I. | pvalue | |
| Age | 1.005 | 0.975–1.037 | 0.727 | |||
| Gender (female) | 2.889 | 1.434–5.823 | 0.003 | 5.027 | 2.001–12.627 | 0.001 |
| NYHA class | 0.798 | 0.472–1.348 | 0.398 | |||
| LVEF | 0.943 | 0.891–0.997 | 0.039 | 0.864 | 0.801–0.933 | <0.001 |
| QRS (ms) | 1.014 | 0.997–1.031 | 0.117 | |||
| AF | 0.242 | 0.088–0.666 | 0.006 | 0.199 | 0.064–0.621 | 0.005 |
| Etiology (ischemic) | 0.790 | 0.424–1.473 | 0.458 | |||
| Hypertension | 0.998 | 0.485–2.053 | 0.996 | |||
| Diabetes mellitus | 0.455 | 0.230–0.899 | 0.023 | 0.331 | 0.143–0.765 | 0.010 |
| Dyslipidemia | 0.802 | 0.432–1.491 | 0.486 | |||
| ACE-is/ARBs | 1.565 | 0.589–4.158 | 0.369 | |||
| Beta-blockers | 1.778 | 0.844–3.345 | 0.130 | |||
| Statins | 0.751 | 0.407–1.386 | 0.360 | |||
| MRAs | 1.220 | 0.666–2.237 | 0.520 | |||
| Diuretics | 0.668 | 0.283–1.575 | 0.357 | |||
| Selvester score | 0.869 | 0.809–0.934 | <0.001 | ∗∗ | ||
| Selvester score ≥7 | 0.335 | 0.179–0.627 | 0.001 | 0.327 | 0.155–0.689 | 0.003 |
| Fragmented QRS | 0.793 | 0.431–1.461 | 0.457 | 1.133 | 0.539–2.381 | 0.742 |
| LVEDD (mm) | 0.976 | 0.939–1.016 | 0.976 | |||
| LVESD (mm) | 0.991 | 0.955–1.028 | 0.635 | |||
| LVEDV (mL) | 1.005 | 0.999–1.012 | 0.127 | |||
| LVESV (mL) | 1.006 | 0.998–1.014 | 0.134 | |||
∗Model 1 includes Selvester score ≥7. ∗∗In model 2, Selvester score is expressed as continuous variable; OR 0.884 (0.813–0.960); p: 0.004. Gender (female), LVEF, AF, diabetes mellitus, and fragmented QRS showed the same OR and p values as in model 1. AF, atrial fibrillation; NYHA, New York Heart Association; LVEF, left ventricular ejection fraction; ACE-I, angiotensin converting enzyme-inhibitors; ARBs, angiotensin receptor blockers; MRAs, mineralocorticoid receptor antagonists; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; LVEDV, left ventricular end-diastolic volume; and LVESV, left ventricular end-systolic volume.