Table 2.
Results of Meta-Analyses of Univariate Hazard Ratios for CMR Measurements
| CMR Measurement | Overall Meta-Analysis |
Mortality Outcome |
Clinical Worsening |
|||
|---|---|---|---|---|---|---|
| HR (95% CI) | Studies (n) | HR (95% CI) | Studies (n) | HR (95% CI) | Studies (n) | |
| RVEF | 0.965 (0.954–0.976) | 20 (1,804) | 0.979 (0.969–0.990) | 8 (1,148) | 0.951 (0.939–0.964) | 12 (656) |
| RVEDVI | 1.007 (1.005–1.010) | 18 (1,744) | 1.006 (1.003–1.008) | 7 (1,118) | 1.010 (1.006–1.013) | 11 (626) |
| RVESVI | 1.010 (1.008–1.013) | 17 (1,676) | 1.009 (1.005–1.012) | 7 (1,118) | 1.013 (1.008–1.018) | 10 (558) |
| RVSVI | 0.989 (0.978–1.001) | 13 (1,328) | 0.984 (0.965–1.004) | 5 (944) | 0.992 (0.979–1.004) | 8 (384) |
| LVEF | 0.992 (0.984–1.000) | 15 (1,561) | 0.994 (0.986–1.003) | 7 (1,118) | 0.980 (0.963–0.998) | 8 (443) |
| LVEDVI | 0.985 (0.974–0.995) | 15 (1,561) | 0.982 (0.968–0.996) | 7 (1,118) | 0.986 (0.969–1.004) | 8 (443) |
| LVESVI | 0.991 (0.979–1.003) | 14 (1,421) | 0.985 (0.967–1.003) | 6 (978) | 0.997 (0.979–1.014) | 8 (443) |
| LVSVI | 0.976 (0.960–0.993) | 11 (1,344) | 0.975 (0.956–0.995) | 7 (1,118) | 0.976 (0.940–1.012) | 4 (226) |
| RVMI | 1.008 (1.001–1.016) | 10 (1,220) | 1.006 (1.000–1.012) | 5 (943) | 1.018 (0.994–1.041) | 5 (277) |
| LVMI | 1.009 (0.997–1.020) | 11 (1,357) | 1.005 (0.995–1.016) | 6 (1,030) | 1.022 (0.991–1.053) | 5 (327) |
CI = confidence interval; CMR = cardiac magnetic resonance; HR = hazard ratio; LVEDVI = left ventricular end-diastolic volume index; LVEF = left ventricular ejection fraction; LVESVI = left ventricular end-systolic volume index; LVMI = left ventricular mass index; LVSVI = left ventricular stroke volume index; RVEDVI = right ventricular end-diastolic volume index; RVEF = right ventricular ejection fraction; RVMI = right ventricular mass index; RVESVI = right ventricular end-systolic volume index; RVSVI = right ventricular stroke volume index.